This chapter aims to advise on first and second choice anti–infective agents for the treatment of common infections in general practice and hospital.

University Hospital Division (UHD) Antimicrobial Prescribing Guidelines are available for advice regarding treatment of severe infections and other specific treatments, for example prophylaxis post splenectomy and dosage adjustments in patients with renal impairment.

The table below provides details on all decisions on medicines since 2002 relating to infections.  It includes all medicines approved by Formulary Committee on FAF1, FAF2 or FAF3 forms. 


Medicines are classified as:
Formulary Drugs
(a) Included in the Lothian Joint Formulary; first or second choice or in the prescribing notes
(b) Additional List: are approved for use in specialist units or when formulary drugs are ineffective, not tolerated or are contraindicated.
Non Formulary Drugs
(a) Not includedrecommended by the SMC but not included in Lothian as suitable alternatives exist or an application has not been made to the Formulary Committee.  (Prescribing of these medicines can be approved through the non-approved medicines route.)
(b) Not recommended: not recommended by the SMC (as not cost effective), therefore, nor by the ADTC/Formulary Committee for use in Lothian.  (Prescribing of these medicines may be approved through the IPTR route, where appropriate.)
Unlicensed medicines are classified by a traffic light system as set out in the ADTC NHS Lothian 'Policy and Procedures for the Use of Unlicensed Medicines' - see full document via this link
RED: Specialist Use only
AMBER: General Use with restrictions
GREEN: Unrestricted General Use
BLACK: Not approved for use